Transgenerational inheritance of longevity: Theoretical framework and empirical evidence

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Transgenerational Inheritance of Longevity: An Epigenetic Phenomenon?

Copyright: © 2013 Vaiserman AM . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Over the past decade, there is substantive evidence that adverse consequences of early-life environmental stresses, such as chem...

متن کامل

Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans

Chromatinmodifiers regulate lifespan in several organisms, raising the question of whether changes in chromatin states in the parental generation could be incompletely reprogrammed in the next generation and thereby affect the lifespan of descendants. The histone H3 lysine 4 trimethylation (H3K4me3) complex, composed of ASH-2,WDR-5 and the histone methyltransferase SET-2, regulates Caenorhabdit...

متن کامل

The growth of business firms: theoretical framework and empirical evidence.

We introduce a model of proportional growth to explain the distribution P(g)(g) of business-firm growth rates. The model predicts that P(g)(g) is exponential in the central part and depicts an asymptotic power-law behavior in the tails with an exponent zeta = 3. Because of data limitations, previous studies in this field have been focusing exclusively on the Laplace shape of the body of the dis...

متن کامل

Transgenerational Inheritance: Perpetuating RNAi.

Reversible changes in gene expression independent of the genetic code can be transmitted from one generation to the next via poorly understood mechanisms. In worms, a histone-modifying enzyme is necessary to keep small RNA-guided transgenerational gene silencing in check.

متن کامل

Transgenerational Epigenetic Inheritance

Recent fi ndings in the emerging fi eld of transgenerational epigenetic inheritance suggest that the lifestyle choices and experiences of an individual have biological implications for offspring not yet conceived. Studies show that diet, drugs, and even social experiences can lead to life-long changes in gene expression. Some changes in gene expression are passed down to future generations. The...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Moscow University Biological Sciences Bulletin

سال: 2016

ISSN: 0096-3925,1934-791X

DOI: 10.3103/s009639251604012x